Emergency Department Management of Patients With Sickle Cell Disease | Points & Pearls
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Emergency Department Management of Patients With Sickle Cell Disease

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Points & Pearls Excerpt

  • Because of worldwide migration trends, persons with sickle cell disease (SCD) can be found in all parts of the world.
  • The primary complications of SCD are severe pain, vaso-occlusive crisis (VOC), splenic sequestration, acute chest syndrome (ACS), priapism, stroke, and infection.

Pain Control

  • IV opioids are typically preferred for rapid and consistent effect, but intranasal fentanyl was found to be noninferior for ED management of pain,74 and may be preferable if there are challenges in IV access, such as in pediatric patients.
  • Table 3 and Table 4 summarize parenteral opioid dosing, and Table 5 and Table 6 summarize dosing for patient-controlled analgesia.3
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Publication Information
Authors

Babette Newman, DO; R. Gentry Wilkerson, MD

Peer Reviewed By

Caroline Freiermuth, MD, MHS, FACEP; Angela Hua, MD, FACEP

Publication Date

August 1, 2024

CME Expiration Date

August 1, 2027    CME Information

CME Credits

4 AMA PRA Category 1 Credits™, 4 ACEP Category I Credits, 4 AAFP Prescribed Credits, 4 AOA Category 2-B Credits.

Pub Med ID: 39042113

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