Points & Pearls Excerpt
- The severity of rectal bleeding depends on the underlying etiology, which can range from benign and self-limiting to life-threatening.
- The differential diagnosis depends on identification of the cause, based on age, comorbid conditions, duration of symptoms, and anatomic, hematologic, and metabolic derangements.
- Table 1 outlines causes of rectal bleeding in adults and children. Table 2 lists medications and toxins associated with rectal bleeding, and Table 3 lists rectal bleeding mimics.
- Most bleeding sources in the colon or distal present as hematochezia, and upper GI bleeds (UGIBs) present with hematemesis and/or melena; however, depending on the cause, this may not always be the case.2,3
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