Infective Endocarditis: Identification and Management in the Emergency Department (Infectious Disease CME) | Digest /topics.php?paction=showTopic&topic_id=423
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Infective Endocarditis: Identification and Management in the Emergency Department (Infectious Disease CME)

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Points and Pearls Excerpt

  • More than 70% of infective endocarditis (IE) cases occur in native valves as a result of platelet aggregation due to valves that are damaged or have altered flow dynamics.
  • Mitral valve prolapse is the most common risk factor and raises risk for IE 8-fold.
  • Impurities in injectable drugs cause valvular damage, typically damaging the tricuspid valve through microtrauma. This area subsequently becomes a nidus for infection.
  • Staphylococcus aureus is the leading cause of IE. Other major causes are Streptococcus viridans, enterococci, and coagulase-negative staphylococci. Blood-culture-negative IE accounts for one-third of cases.
  • IE should be considered in any patient with > 1 week of fever that is consistent or intermittent.

Most Important References

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Publication Information
Authors

Anthony J. Hackett, DO, FAAEM, FACEP; Jonathan Stuart, DO, MS

Peer Reviewed By

Katrina Harper-Kirksey, MD; Evan Leibner, MD, PhD

Publication Date

September 1, 2020

CME Expiration Date

September 1, 2023   

Pub Med ID: 32805090

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