Anaphylaxis in Pediatric Patients: Early Recognition and Treatment Are Critical for Best Outcomes (Pharmacology CME) | Digest
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Anaphylaxis in Pediatric Patients: Early Recognition and Treatment Are Critical for Best Outcomes

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Points and Pearls Excerpt

  • Anaphylaxis is an acute, systemic allergic reaction that can lead to life-threatening symptoms within minutes to hours. Treatment with intramuscular (IM) epinephrine should be initiated early, even in uncertain cases, as it may prevent progression to respiratory failure or cardiac arrest.
  • Most patients have mucocutaneous symptoms (urticaria, flushing, angioedema) and respiratory complaints. Diagnosis can be challenging in patients who lack cutaneous findings. Subjective symptoms of dyspnea should not be discounted, especially in patients with a history of severe anaphylaxis.
  • Anaphylaxis in infants can present with nonspecific symptoms such as facial flushing, vomiting, and loose stool. Concurrent tachycardia or hypotension should raise suspicion for possible anaphylaxis.

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Publication Information
Authors

Jeranil Nunez, MD; Genevieve Santillanes, MD, FAAP, FACEP

Peer Reviewed By

Bharati Beatrix Bansal, MD; Ronna Campbell, MD, PhD

Publication Date

June 2, 2019

Pub Med ID: 31124642

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