Points and Pearls Excerpt
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Envenomation by Latrodectus mactans (black widow spiders) can result in significant pain and hyperadrenergic symptoms. Treatment should first be focused on ensuring adequate administration of opioids and benzodiazepines.
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Use of Latrodectus antivenom is generally not considered first-line therapy because of the relatively high rate of immediate (anaphylactoid) or delayed (serum sickness) allergic reactions.
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Because toxicity from Loxosceles (brown recluse) bites primarily manifests as necrotic dermal lesions, various soft-tissue infections are often incorrectly ascribed to envenomation from this spider.
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Patients envenomated by a Loxosceles spider should be observed for necrotic lesions and systemic effects. Hemolysis should be treated with corticosteroids.
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Massive hymenoptera envenomation can result in multisystem organ involvement. Treatment with corticosteroids is indicated even though the reaction is not IgE-mediated.
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