Current Concepts in Ketamine Therapy in the Emergency Department (Pharmacology CME and Pain Management CME) | Points & Pearls
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Current Concepts in Ketamine Therapy in the Emergency Department (Pharmacology CME and Pain Management CME)

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Points & Pearls Excerpt

Procedural Sedation and Anesthesia (PSA)

  • Dissociative-dose ketamine is often superior to alternative agents for PSA, as the patient is completely unaware of painful stimuli while airway, breathing, and circulation are usually maintained.
  • Ketamine can cause hypertension, muscle rigidity, and psychiatric distress during PSA; these adverse effects are usually effectively treated with small doses of propofol or midazolam as needed.
  • A patient who develops agitation shortly after induction during ketamine PSA is likely partially dissociated because they were under-dosed.
  • Psychiatric distress on emergence from ketamine PSA is less likely if the patient receives adequate analgesia prior, is coached on the anticipated effects, and emerges in a quiet environment.
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Publication Information
Author

Reuben J. Strayer, MD

Peer Reviewed By

Natalie Kreitzer, MD, MS; Andrew Schmidt, DO, MPH

Publication Date

May 1, 2024

CME Expiration Date

May 1, 2027    CME Information

CME Credits

4 AMA PRA Category 1 Credits™, 4 ACEP Category I Credits, 4 AAFP Prescribed Credits, 4 AOA Category 2-B Credits.
Specialty CME Credits: Included as part of the 4 credits, this CME activity is eligible for 4 Pharmacology CME credits and 1 Pain Management CME credit, subject to your state and institutional approval.

Pub Med ID: 38639638

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