Angioedema in the Emergency Department: An Evidence-Based Update (Pharmacology CME) | Podcast
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Angioedema in the Emergency Department: An Evidence-Based Update (Pharmacology CME)

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Date: 01/01/2023 | Length: 47:52

 

Show Notes

Pathophysiology: Non-pitting edema of respiratory or GI tract.

  • Histamine meditated , bradykinin mediated or idiopathic
  • Acquired, inherited, or idiopathic
  • Do they present differently ? (urticaria, speed of onset)

Histamine Mediated

  • Most common form. 40-70%
  • Can be triggered by NSAIDs
  • Can be induced by physical mechanism like cold, vibration
  • Is rash a reliable method of distinguishing the types?

Bradykinin Mediated

  • May progress slowly
  • Can be inherited or acquired
  • Common triggers include ACE inhibitors and TPA

Table 1 Differential Diagnosis

Prehospital Care

  • Protect Airway
  • Epi, Steroids, Antihistamines
  • Avoid CPAP

ED History

  • Figure 2 - distinguishing characteristics of Histamine vs Bradyknin mediated

ED Exam

  • Importance of repetitive exams
  • Airway examination
  • Laryngoscopy?

Diagnostics

  • Figure 6 flow diagram of ED workup
  • Labs
  • Imaging

Treatment

  • Airway - intubation
  • Medication

Special Populations

  • Pediatric
  • Pregnant / Lactating patients

Controversies

  • TXA

Disposition

 

 

Meet the Host

Sam Ashoo, MD, FACEP

Dr. Ashoo is a practicing emergency physician, board-certified in emergency medicine and clinical informatics. Join him as he takes you through the October 2022 issue of Emergency Medicine Practice: Angioedema in the Emergency Department: An Evidence-Based Update (Pharmacology CME)


About The Podcast

Get quick-hit summaries of hot topics in emergency medicine. EMplify summarizes evidence-based reviews in a monthly podcast. Highlights of the latest research published in EB Medicine's peer-reviewed journals educate and arm you for life in the ED.

 

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Publication Information
Authors

Prayag Mehta, MD; Nikola Milanko, MD; Jedediah Leaf, MD; Joshua Kern, MD

Peer Reviewed By

Charlotte Goldfine, MD; Ashley Booth Norse, MD

Publication Date

October 1, 2022

CME Expiration Date

October 1, 2025    CME Information

CME Credits

4 AMA PRA Category 1 Credits™, 4 ACEP Category I Credits, 4 AAFP Prescribed Credits, 4 AOA Category 2-A or 2-B Credits.
Specialty CME Credits: Included as part of the 4 credits, this CME activity is eligible for 4 Pharmacology CME credits.

Pub Med ID: 36121764

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Publication Information
Authors

Prayag Mehta, MD; Nikola Milanko, MD; Jedediah Leaf, MD; Joshua Kern, MD

Peer Reviewed By

Charlotte Goldfine, MD; Ashley Booth Norse, MD

Publication Date

October 1, 2022

CME Expiration Date

October 1, 2025

CME Credits

4 AMA PRA Category 1 Credits™, 4 ACEP Category I Credits, 4 AAFP Prescribed Credits, 4 AOA Category 2-A or 2-B Credits.
Specialty CME Credits: Included as part of the 4 credits, this CME activity is eligible for 4 Pharmacology CME credits.

Pub Med ID: 36121764

Get Permission

CME Information

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