The term acute kidney injury has replaced the previously used term, acute renal failure. AKI better represents the spectrum of disease between normal renal function and the absence of renal function, which includes early renal injury that precedes changes in urine output and metabolic derangements. AKI represents a continuum of renal disease that can lead to a progressive loss of renal function.
Currently, there are numerous published definitions of AKI in the literature, and consensus has yet to be reached about which classification to use in the clinical setting. A universally accepted definition and categorization of the disease would be helpful for research and for making recommendations on this topic. Furthermore, consensus on this topic could help to identify children at risk for CKD.
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