Etiology And Pathophysiology | Altered Level Conciousness

<< Altered Level of Consciousness: Evidence-Based Management in the Emergency Department (Pharmacology CME)

Etiology And Pathophysiology

The awake state of humans is thought to be largely affected by the ascending reticular activating system (ARAS). The ARAS is a network of neurons located in the midbrain, pons, and medulla, and it is responsible for receiving sensory input and modulating wakefulness and alertness. ALOC can result from focal lesions within the ARAS, or in areas affecting the ARAS, and, in turn, can affect a person’s state of consciousness.2,8 

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