There is a lack of evidence substantiating novel therapies for the treatment of ischemic priapism. Most data are confined to case reports or limited studies. For example, intracavernosal methylene blue has been shown as a potential therapy for ischemic priapism in 2 studies,66,67 but, to our knowledge, no comparative studies between methylene blue and phenylephrine exist. In a case report, a 4 mg/kg intramuscular dose of ketamine was used to treat priapism caused by dexmethylphenidate in a pediatric patient.68
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