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<< Pelvic Inflammatory Disease: Diagnosis and Treatment in the Emergency Department (Pharmacology CME)

Controversies And Cutting Edge

Mycoplasma genitalium

M genitalium is a fastidious, slow-growing organism that was first isolated from men with non–gonococcal urethritis. A recent meta-analysis confirms that M genitalium infection is associated with an increased risk of cervicitis and PID as well as preterm birth and spontaneous abortion.120 In contrast to C trachomatis, M genitalium infection is generally asymp-tomatic and appears to be less likely to progress to PID.18 Prevalence of M genitalium is similar to the prevalence of C trachomatis in young women aged 18 to 27 years (approximately 1%).121 Notably, the prevalence is considerably greater among men who have sex with men (13%), patients who have had 3 or more sexual partners in the last 12 months (11%), and patients with HIV.51,122,123

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