Patients At High Risk For Severe Disease
Special consideration should be given to patients who are at risk for severe disease. Infants aged < 1 year, immunocompromised patients, and pregnant women can have greater morbidity and mortality when infected with any of these viruses. Varicella infection may also result in severe disease in adults aged > 20 years. While 5% of varicella cases occur in adults, adult infections (especially in patients who develop pneumonia) account for 35% of the mortality from this disease.62 Atopic diseases may predispose patients to severe manifestations of varicella, especially bacterial superinfection.62
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