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<< Vaccine-Preventable Diseases In Pediatric Patients: A Review Of Measles, Mumps, Rubella, And Varicella

Special Circumstances

Patients At High Risk For Severe Disease

Special consideration should be given to patients who are at risk for severe disease. Infants aged < 1 year, immunocompromised patients, and pregnant women can have greater morbidity and mortality when infected with any of these viruses. Varicella infection may also result in severe disease in adults aged > 20 years. While 5% of varicella cases occur in adults, adult infections (especially in patients who develop pneumonia) account for 35% of the mortality from this disease.62 Atopic diseases may predispose patients to severe manifestations of varicella, especially bacterial superinfection.62

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