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<< Managing Acute Complications Of Sickle Cell Disease In Pediatric Patients

Introduction And Epidemiology

Sickle cell disease (SCD) refers to a family of genetic blood disorders caused by the sickling of red blood cells secondary to atypical hemoglobin molecules, known as hemoglobin S (HbS). This disease is seen primarily in individuals of African, Indian, Mediterranean, or Saudi Arabian ancestry.Annually, 200,000 children are born with SCD worldwide. Ninety percent of these births are in sub-Saharan Africa. In the United States, 1 in 2474 births are children with SCD. The national prevalence is between 70,000 to 140,000 patients, mostly in those of African ancestry.2

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Last Modified: 07/23/2017
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