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Propylene Glycol Toxicity

Etiology And Pathophysiology

Propylene glycol is a sweet, viscous liquid used in some antifreezes as an “environmentally friendly” or “pet friendly” alternative to ethylene glycol, and is also used as a diluent for foods, cosmetics, and pharmaceuticals such as lorazepam, esmolol, phenobarbital, nitroglycerin, diazepam, and phenytoin.1,16,137-142 Toxicity is most often from iatrogenic exposure in patients receiving infusions.

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