<< Cervical Spinal Injury In Pediatric Blunt Trauma Patients: Management In The Emergency Department (Trauma CME)

Controversies And Cutting Edge

There have been several low-quality studies on local cooling of the spinal cord with mixed and difficult-to-interpret results.73-76 Interestingly, a recent phase I clinical trial of moderate systemic hypothermia (33°C) in adults showed improved neurologic outcomes in the hypothermia group.77 At 1-year follow-up, 6 of 14 hypothermia patients converted from complete to incomplete injury status compared to 3 of 14 in the control group. These numbers are encouraging, considering the general reported recovery rate is about 20%. A relatively small number of patients was examined in this study and, therefore, a larger prospective trial is needed to better evaluate this therapy.

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