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<< The HIV-Infected Adult Patient in the Emergency Department: The Changing Landscape of Disease (Pharmacology CME)

Key Points

  • A thorough history should include the patient’s most recent CD4 count, CD4 nadir, viral load, and a list of the patient’s medications.
  • HAART (especially PIs) increase triglycerides and LDL (low-density lipoprotein) and lower HDL (high-density lipoprotein) levels, causing higher risk of coronary artery disease.
  • Systemic inflammatory response associated with chronic HIV leads to coronary artery disease, hypercoagulability, and venous thromboembolism.
  • Ritonavir increases bioavailability of corticosteroids and can lead to iatrogenic Cushing syndrome.

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