Allergic reactions occur when hypersensitivity to a foreign protein or antigen that normally would not be deleterious is acquired. On the spectrum of allergic responses, anaphylaxis is a profound reaction. Historically, anaphylaxis has lacked a standard, universally accepted definition, which has hampered the ability to consistently diagnose it. The National Institute of Allergy and Infectious Diseases and the Food Allergy and Anaphylaxis Network consensus defines anaphylaxis clinically as a continuum of a constellation of acute symptoms affecting multiple systems in the body after exposure to an allergen.
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