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<< Evidence-Based Hospital Management Of Patients With Heart Failure With Preserved Ejection Fraction

Introduction

Heart failure is a clinical syndrome characterized by frequent hospitalizations, high mortality, poor quality of life, multiple comorbidities, and complex treatment regimens.1 Over 5 million Americans have heart failure, of which approximately 50% have normal ejection fraction.2-4 The proportion of patients with the diagnosis of heart failure with preserved ejection fraction (HF-PEF) has increased over time while the rate of death from this disorder remains unchanged.3 Heart failure, in general, is the underlying reason for 6.5 million hospital days each year,5 and since the etiology, pathophysiology, and treatment of heart failure with preserved ejection fraction (PEF) and reduced ejection fraction (REF) are different, it is important for the hospitalist physician to understand the difference in order to deliver the appropriate therapy.

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