<< Hospital Management Of Hypertension: Urgencies And Emergencies

Special Clinical Presentations

In the first 24 hours after an acute ischemic stroke, the American Stroke Association and others recommend cautious reduction of blood pressure (between 10% and 15%) if systolic pressure is > 220 mm Hg or diastolic pressure is > 120 mm Hg.59-63 This recommendation is based on both physiological data as well as epidemiologic studies showing that abrupt blood pressure reduction in the setting of impaired autoregulation worsens perfusion in areas surrounding the initial ischemic zone (penumbra) and results in dire outcomes.43

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