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<< Sickle Cell Disease: A Comprehensive Review Of Inpatient Management

Etiology And Pathophysiology

In a SCD patient who inherits a point mutation on the sixth position of the B-globin chain from both parents, sickle cell hemoglobin (HbS) is the predominant form of hemoglobin. HbS forms long, inflexible chains that give rise to characteristic sickled red blood cells.

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Last Modified: 07/23/2017
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