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<< Sickle Cell Disease: A Comprehensive Review Of Inpatient Management

Introduction

The first formal report of sickle cell disease (SCD) was made more than a century ago by Chicago cardiologist Dr. James Herrick.1 Since then, there has been a great focus on gaining an understanding of the management of patients with various manifestations of SCD. This can be attributed to a combination of basic and clinical research, a growing emphasis on public health, and greater opportunities for community management of the disease.2 Patients with SCD have clearly benefited from this, with notable improvements in morbidity and mortality. Improvements in survival of SCD patients into adulthood can be attributed to the use of prophylactic penicillin and pneumococcal vaccination to prevent severe pneumococcal infection in pediatric patients and the widespread implementation of newborn screening.2,3

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Last Modified: 07/23/2017
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