Since the etiology of Kawasaki disease remains unclear, the goals of treatment focus on the prevention of coronary artery aneurysm development. Early identification and treatment of Kawasaki disease has been shown to reduce the development of coronary artery aneurysms. Treatment should be started as soon as a diagnosis of Kawasaki disease is made. Current recommendations suggest treatment should be given within 10 days of the onset of fever, and, ideally, within 7 days of the onset of fever.5 Initial treatment in the United States generally includes IVIG in combination with high-dose aspirin.75
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