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<< Evidence-Based Management Of Kawasaki Disease In The Emergency Department

Introduction

Kawasaki disease is rarely fatal, but virtually all deaths result from cardiac sequelae. In fact, this disease has now surpassed rheumatic heart disease as the leading acquired heart disease in children in the United States.5 Coronary artery aneurysms occur in 15% to 25% of untreated children. Coronary artery aneurysm has been known to lead to myocardial infarction, ischemic heart disease, and sudden cardiac death. Peak mortality occurs 15 to 45 days after the development of fever. However, sudden cardiac death has been documented years after the diagnosis of Kawasaki disease. In-hospital mortality is currently estimated to be 0.17% in the United States.7

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