Several factors must be considered when choosing antibiotic therapy. Indiscriminate use of “big gun” broad-spectrum antibiotics is not advised due to high cost, collateral damage to the patient’s normal bacterial biome, and resistance development. Indiscriminate use of broad-spectrum antibiotics is associated with higher incidence of general resistance in a community and with Clostridium difficile infection. National guidelines, books or pamphlets, or mobile device applications are not likely to reflect all community environments.8,77-79
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