<< Pediatric Herpes Simplex Virus Infections: An Evidence-Based Approach To Treatment

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Eczema Herpeticum

Eczema herpeticum, also known as Kaposi-Juliusberg varicelliform eruption, is a dermatologic emergency presenting as a diffuse HSV skin infection, typically in children or young adults with eczema.101,102 It is characterized by a diffuse eruption that quickly develops from vesicles and pustules that become crusted over.101 (See Figure 3.) Fever, malaise, and regional lymphadenopathy are often present.93,101-103 The severity is variable, ranging from a mild transient disease to a fulminant fatal disorder.101,102 Mortality rates prior to the advent of antiviral medications were estimated to be between 10% and 50%,101 but today, mortality rates are < 10%.104 Early identification and treatment of eczema herpeticum is important, as it may progress to disseminated disease if untreated.105

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