<< Pediatric Herpes Simplex Virus Infections: An Evidence-Based Approach To Treatment

Differential Diagnosis

The differential diagnosis for herpes infections varies greatly depending upon presentation of the infection. Table 1 summarizes the differential diagnosis when evaluating for HSV infections.


The differential diagnosis for neonatal herpes includes serious infections (such as bacterial sepsis, viral pneumonia, and hepatitis) as well as benign rashes (such as erythema toxicum and pustular melanosis). The age of the patient and the appearance of the lesions, along with other clinical symptoms, may aid in narrowing the differential diagnosis.

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