AF and AFL are supraventricular tachycardias that arise from disorganized or abnormal atrial depolarization. Atrial fibrosis and loss of atrial muscle mass are the most frequent histopathological changes in AF. Electrical remodeling occurs, resulting in multiple reentry circuits or rapidly firing atrial foci and shortening of atrial refractoriness and action potential, thus contributing to the maintenance of AF.8
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