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<< Critical Care Of Severe Thermal Burn Injury (Trauma CME)

Burn Injury As A Member Of The Profound Inflammatory Family

Burn injury can be conceptualized as 2 distinct temporal processes. Acutely, the primary burn causes variable structural damage to exposed tissues with severity dependent on the type, duration, and intensity of exposure. Of far graver concern, however, is the potential development of a secondary, multifactorial inflammatory response – burn shock – as a consequence of the release of various local and systemic vasoactive mediators that compromise capillary integrity and facilitate fluid extravasation into the extravascular space.

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