Several authors have attempted to predict the risk of airway compromise in angioedema attacks. Ishoo et al performed a single-center retrospective review of patients admitted over an 11-year period with angioedema due to all causes.107 They found that the following factors were associated with an increased risk of need for definitive airway: voice change, hoarseness, stridor, and dyspnea. Patients in the study by Ishoo et al were categorized according to the anatomic location of the edema.107
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