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<< Evidence-Based Management Of Sickle Cell Disease In The Emergency Department

Introduction

Introduction

Sickle cell disease is the most common genetic disease in America,1 affecting approximately 100,000 individuals.2 Since the discovery of SCD 100 years ago, our understanding of the disease has changed dramatically. Research has revealed that the genetic mutations underlying SCD not only result in sickle-shaped red blood cells (RBCs) but also completely alter the rheologic properties of the blood, causing
clinical manifestations in every organ system. Despite major advances in our understanding of the disease, literature to guide clinical decisions in the treatment of SCD is sorely lacking. This issue of Emergency Medicine Practice presents a synopsis of the latest evidence regarding the pathophysiology, diagnosis, and treatment of emergent complications of SCD.

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Last Modified: 07/23/2017
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