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<< Current Guidelines For Sickle Cell Disease: Management Of Acute Complications


  1. Benjamin LJ, Dampier CD, Jacox A, et al. Guideline for the management of acute and chronic pain in sickle-cell disease. American Pain Society. 1999. (Clinical Guideline)
  2. Davies SC, Brozović M. Acute admissions of patients with sickle cell disease who live in Britain. Br Med J (Clin Res Ed). 1987 May 9;294(6581):1206-1208. PMID: 3109583 (Retrospective; 211 patients)
  3. Platt OS, Thorington BD, Brambilla DJ, et al. Pain in sickle cell disease. Rates and risk factors. N Engl J Med. 1991 Jul 4;325(1):11-16. PMID: 1710777 (Prospective; 3578 patients)
  4. Benjamin L. Pain management in sickle cell disease: palliative care begins at birth? Hematology Am Soc Hematol Educ Program. 2008:466-474. PMID: 19074128 (Comment)
  5. Benjamin LJ, Swinson GI, Nagel RL. Sickle cell anemia day hospital: an approach for the management of uncomplicated painful crises. Blood. 2000 Feb 15;95(4):1130-1136. PMID:10666181 (Prospective; 5166 episodes)
  6. Allon M, Lawson L, Eckman JR, Delaney V, Bourke E. Effects of nonsteroidal antiinflammatory drugs on renal function in sickle cell anemia. Kidney Int. 1988 Oct;34(4):500-506. PMID: 3199668 (Prospective Case Control; 27 patients)
  7. Hudcova J, McNicol E, Quah C, Lau J, Carr DB. Patient controlled opioid analgesia versus conventional opioid analgesia for postoperative pain. Cochrane Database Syst Rev. 2006;(4):CD003348. doi:10.1002/14651858.CD003348.pub2.
  8. Vichinsky EP, Neumayr LD, Earles AN, et al. Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. N Engl J Med. 2000 Jun 22;342(25):1855-1865. Erratum in: N Engl J Med. 2000 Sep 14;343(11):824. PMID: 10861320 (Prospective; 538 patients)
  9. US Department of Health and Human Services, National Institutes of Health, National Heart Lung and Blood Institute. The management of sickle cell disease. NIH Publication No. 02-2117. http://www.nhlbi.nih.gov/health/prof/blood/sickle/index.htm. Fourth edition, revised June 2002. Accessed October 13, 2009. (Clinical Guideline)
  10. Leikin SL, Gallagher D, Kinney TR, et al. Mortality in children and adolescents with sickle cell disease. Cooperative Study of Sickle Cell Disease. Pediatrics. 1989;84:500-508. (Prospective; 2824 patients)
  11. Serjeant GR, Serjeant BE, Thomas PW, et al. Human parvovirus infection in homozygous sickle cell disease. Lancet. 1993;341:1237-1240. (Prospective; 547 patients)
  12. Goldstein AR, Anderson MJ, Serjeant GR. Parvovirus associated aplastic crisis in homozygous sickle cell disease. Arch Dis Child. 1987;62:585-588. (Retrospective; 314 patients)
  13. Lascari AD, Pearce JM. Use of gamma globulin and erythropoietin in a sickle cell aplastic crisis. Clin Pediatr. 1994;33:117-119. PMID: 7515339
  14. Anand A, Gray ES, Brown T, et al. Human parvovirus infection in pregnancy and hydrops fetalis. N Engl J Med. 1987;316:183-186. (Retrospective; 6 patients)
  15. Ohene-Frempong K, Weiner SJ, Sleeper LA, et al. Cerebrovascular accidents in sickle cell disease: rates and risk factors. Blood. 1998;91:288-294. (Prospective; 4082 patients)
  16. Swerdlow PS. Red cell exchange in sickle cell disease. Hematology Am Soc Hematol Educ Program. 2006:48-53. (Review)
  17. Clarkson JG. The ocular manifestations of sickle cell disease: a prevalence and natural history study. Trans Am Ophthalmol Soc.1992;90:481-504. (Comment)
  18. Emre U, Miller ST, Rao SP, et al. Alveolar-arterial oxygen gradient in acute chest syndrome of sickle cell disease. J Pediatr.1993;123:272-275. (Retrospective; 44 patients)
  19. Emond AM, Collis R, Darvill D, et al. Acute splenic sequestration in homozygous sickle cell disease: natural history and management. J Pediatr. 1985;107:201-206. (Retrospective; 308 patients)
  20. Topley JM, Rogers DW, Stevens MCG, et al. Acute splenic sequestration and hypersplenism in the first five years in homozygous sickle cell disease. Arch Dis Child. 1981;56:765-769. (Retrospective; 216 patients)
  21. Mantadakis E, Ewalt DH, Cavender JD, et al. Outpatient penile aspiration and epinephrine irrigation for young patients with sickle cell anemia and prolonged priapism. Blood. 2000;95:78-82. (Prospective; 15 patients)

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