Ebola Virus Disease: Epidemiology, Clinical Presentation, and Diagnostic and Therapeutic Modalities (Pharmacology CME)
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Ebola Virus Disease: Epidemiology, Clinical Presentation, and Diagnostic and Therapeutic Modalities (Pharmacology CME) - $49.00

Publication Date: July 2016 (Volume 13, Number 7)

CME Credits: 4 AMA PRA Category 1 Credits™, 4 ACEP Category I Credits, 4 AAFP Prescribed Credits, 4 AOA Category 2-A or 2-B Credits. CME expires 7/1/2019

Specialty CME Credits: Included as part of the 4 credits, this CME activity is eligible for 0.5 Pharmacology CME credits, subject to your state and institutional approval.

Marlie Dulaurier, MD
Pediatric Emergency Medicine, Nationwide Children’s Hospital; Assistant Professor of Pediatrics, The Ohio State University, Columbus, OH
Katherine Moyer, DO
Pediatric Infectious Diseases Fellow, Nationwide Children’s Hospital, Columbus, OH
Rebecca Wallihan, MD
Assistant Professor of Clinical Pediatrics, Section of Infectious Diseases, Nationwide Children’s Hospital and The Ohio State University College of Medicine, Columbus, OH
Peer Reviewers
Carl Eriksson, MD, MPH
Assistant Professor, Pediatric Critical Care, Department of Pediatrics, Oregon Health & Science University, Portland, OR
Braden Hexom, MD
Associate Professor, Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY
Shobhit Jain, MD, FAAP
Assistant Professor of Pediatrics, Division of Emergency Medicine, Children's Mercy Hospitals and Clinics, Kansas City, MO


Ebola virus disease (EVD) is a severe multisystem disease. Prehospital personnel, hospitals, and clinicians must be prepared to provide care for patients with EVD, with special attention to rigorous infection control in order to limit the spread of infection. Children with EVD are an especially challenging population, as the initial symptoms are nonspecific and difficult to differentiate from several common infections. For children presenting with a syndrome consistent with EVD, it is extremely important that healthcare workers identify epidemiologic risk factors, such as recent travel to an affected country or exposure to a patient with suspected or known EVD. Given the high morbidity and mortality of this disease, clinical efforts should focus on early diagnosis, appropriate infection control, and supportive care.

Excerpt From This Issue

A 4-year-old girl presents to the ED with a 4-day history of tactile fever, headache, malaise, joint pain, difficulty breathing, large-volume diarrhea, and nonbloody, nonbilious emesis. She lives at home with her parents and 8-year-old sister. She emigrated from Liberia 2 weeks ago. On examination, she is pale, ill-appearing, and lethargic. Her vital signs are: temperature, 40.4ºC (104.7ºF); respiratory rate, 40 breaths/min; heart rate, 185 beats/ min; blood pressure, 72/43 mm Hg; and oxygen saturation, 86% on room air. Dried blood is noted in her right nare. Her lung sounds are normal, but tachypnea with moderate retractions are present. She is tachycardic with a normal rhythm and a capillary refill of 4 seconds. Her abdomen is soft and mildly tender diffusely, but no distention or rebound is present. Her extremities are cool to the touch and mottled, but no rash is noted. She moans in response to the examination.

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