LLSA 2020 - Review 5: Necrotizing Soft-Tissue Infections

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Review 5: Necrotizing Soft-Tissue Infections


Leila L. PoSaw, MD, MPH, FACEP
Emergency Ultrasound Director, Department of Emergency Medicine, Jackson Memorial Hospital, Miami, FL

About this Review

The objective of this article is to review necrotizing soft-tissue infections, including classification, clinical findings, diagnostic testing, and recommended management. The article also provides great detail on the epidemiology of these infections. The authors gathered evidence from 100 applicable articles published through 2016.

  1. Article Citation
  2. Synopsis
  3. Quick Quiz
  4. Discussion
    1. Definition and Classification
    2. Classification of Necrotizing Fasciitis
      1. Necrotizing Fasciitis Type I
      2. Necrotizing Fasciitis Type II
      3. Necrotizing Fasciitis Type III
      4. Other Pathogens Causing Necrotizing Skin Infections
    3. Diagnosis of Necrotizing Skin Infections
      1. Clinical Findings
      2. Imaging
      3. Tissue Biopsy, Histologic Testing, and Gram Stain
      4. Serum Analysis
      5. Laboratory Risk Indicator for Necrotizing Fasciitis Scoring System
    4. Treatment
      1. Surgical Intervention
      2. Pharmacologic Treatment
      3. Management of Associated Critical Problems
      4. Adjunctive Treatment
  5. Critique
  6. Key Points
  7. Editor’s Note
  8. Quick Quiz Answer
  9. Original Article

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