Batabyal RA, O’Connell K. Improving management of severe asthma: BiPAP and beyond. Clin Ped Emerg Med. 2018;19(1):69-75.
Severe asthma exacerbations are the most common medical emergencies in children, and emergency medicine physicians must be able to manage these patients quickly and effectively. When exacerbations are refractory to standard, first-line treatments, alternative therapies such as intravenous magnesium sulfate and positive pressure ventilation can be considered. This article reviews an array of alternative treatments in the context of the 2007 National Asthma Education and Prevention Program (NAEPP) guidelines and the 2017 Global Initiative for Asthma guidelines.