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<< Acute Spinal Injuries: Assessment and Management

References

Evidence-based medicine requires a critical appraisal of the literature based upon study methodology and number of subjects. Not all references are equally robust. The findings of a large, prospective, randomized, and blinded trial should carry more weight than a case report.

To help the reader judge the strength of each reference, pertinent information about the study, such as the type of study and the number of patients in the study, will be included in bold type following the reference, where available. In addition, the most informative references cited in the paper, as determined by the authors, will be noted by an asterisk (*) next to the number of the reference.

  1. Harvey C, Wilson SE, Greene CG, Berkowitz M, Stripling TE. New estimates of the direct costs of traumatic spinal cord injuries: results of a nationwide survey. Paraplegia. Dec 1992;30(12):834-850. (Observational)
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  4. NSCISC. SPINAL CORD INJURY Facts and Figures at a Glance. Birmingham, Alabama: National Spinal Cord Injury Statistical Center; 2003. (Database)
  5. Bracken MB. Steroids for acute spinal cord injury. Cochrane Database Syst Rev. 2002(3):CD001046. (Systematic Review)
  6. * Kwan I BF, Roberts I. On behalf of the WHO Pre-Hospital Trauma Care Steering Committee. Spinal Immobilization for Trauma Patients. Cochrane Database Syst Rev. 2003(3). (Systematic Review)
  7. Guidelines for management of acute cervical spinal injuries. Introduction. Neurosurgery. Mar 2002;50(3 Suppl):S1. (Systematic Review)
  8. Bagley LJ. Imaging of spinal trauma. Radiol Clin North Am. Jan 2006;44(1):1-12, vii. (Systematic Review)
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  10. Sekhon LH, Fehlings MG. Epidemiology, demographics, and pathophysiology of acute spinal cord injury. Spine. Dec 15 2001;26(24 Suppl):S2-12. (Systematic Review)
  11. * Goldberg W, Mueller C, Panacek E, Tigges S, Hoffman JR, Mower WR. Distribution and patterns of blunt traumatic cervical spine injury. Ann Emerg Med. Jul 2001;38(1):17-21. (Prospective Observational – 34069 patients)
  12. Hadley MN. Guidelines for management of acute cervical spinal injuries. Introduction. Neurosurgery. Mar 2002;50(3 Suppl):S7-S20. (Editorial)
  13. Brunette DD, Rockswold GL. Neurologic recovery following rapid spinal realignment for complete cervical spinal cord injury. J Trauma. Apr 1987;27(4):445-447. (Case Report)
  14. Burney RE, Waggoner R, Maynard FM. Stabilization of spinal injury for early transfer. J Trauma. Nov 1989;29(11):1497-1499. (Retrospective Review)
  15. Hachen HJ. Emergency transportation in the event of acute spinal cord lesion. Paraplegia. May 1974;12(1):33-37.
  16. Geisler WO, Wynne-Jones M, Jousse AT. Early management of the patient with trauma to the spinal cord. Med Serv J Can. Jul-Aug 1966;22(7):512-523.
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  18. Totten VY, Sugarman DB. Respiratory effects of spinal immobilization. Prehosp Emerg Care. Oct-Dec 1999;3(4):347-352. (Experimental – 39 Volunteers)
  19. Podolsky S, Baraff LJ, Simon RR, Hoffman JR, Larmon B, Ablon W. Efficacy of cervical spine immobilization methods. J Trauma. Jun 1983;23(6):461-465. (Experimental– 25 Volunteers)
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  22. McHugh TP, Taylor JP. Unnecessary out-of-hospital use of full spinal immobilization. Acad Emerg Med. Mar 1998;5(3):278-280. (Prospective Observational – 129 patients)
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  25. Bauer D, Kowalski R. Effect of spinal immobilization devices on pulmonary function in the healthy, nonsmoking man. Ann Emerg Med. Sep 1988;17(9):915-918. (Prospective Observational – 15 Volunteers)
  26. Cordell WH, Hollingsworth JC, Olinger ML, Stroman SJ, Nelson DR. Pain and tissue-interface pressures during spine-board immobilization. Ann Emerg Med. Jul 1995;26(1):31-36. (Experimental – 20 Volunteers)
  27. Davies G, Deakin C, Wilson A. The effect of a rigid collar on intracranial pressure. Injury. Nov 1996;27(9):647-649. (Experimental – 19 Volunteers)
  28. Hewitt S. Skin necrosis caused by a semi-rigid cervical collar in a ventilated patient with multiple injuries. Injury. Jul 1994;25(5):323-324. (Case Report)
  29. Vickery D. The use of the spinal board after the pre-hospital phase of trauma management. Emerg Med J. Jan 2001;18(1):51-54. (Systematic Review)
  30. Morris CG, McCoy EP, Lavery GG. Spinal immobilisation for unconscious patients with multiple injuries. Bmj. Aug 28 2004;329(7464):495-499. (Systemtatic Review)
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  32. Domeier RM, Swor RA, Evans RW, et al. Multicenter prospective validation of prehospital clinical spinal clearance criteria. J Trauma. Oct 2002;53(4):744-750. (Prospective Observational – 8975 patients)
  33. * Domeier RM, Frederiksen SM, Welch K. Prospective performance assessment of an out-of-hospital protocol for selective spine immobilization using clinical spine clearance criteria. Ann Emerg Med. Aug 2005;46(2):123-131. (Prospective Performance Assessment – 13483 patients)
  34. Baez AA, Schiebel N. Evidence-based emergency medicine/systematic review abstract. Is routine spinal immobilization an effective intervention for trauma patients? Ann Emerg Med. Jan 2006;47(1):110-112. (Systematic Review)
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  38. Hastings RH, Kelley SD. Neurologic deterioration associated with airway management in a cervical spine-injured patient. Anesthesiology. Mar 1993;78(3):580-583. (Case Report)
  39. Muckart DJ, Bhagwanjee S, van der Merwe R. Spinal cord injury as a result of endotracheal intubation in patients with undiagnosed cervical spine fractures. Anesthesiology. Aug 1997;87(2):418-420. (Case Report)
  40. Gerling MC, Davis DP, Hamilton RS, et al. Effects of cervical spine immobilization technique and laryngoscope blade selection on an unstable cervical spine in a cadaver model of intubation. Ann Emerg Med. Oct 2000;36(4):293-300. (Experimental)
  41. Hastings RH, Vigil AC, Hanna R, Yang BY, Sartoris DJ. Cervical spine movement during laryngoscopy with the Bullard, Macintosh, and Miller laryngoscopes. Anesthesiology. Apr 1995;82(4):859-869. (Randomized Controlled Trial – 35 patients)
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  47. Cadoux CG, White JD, Hedberg MC. High-yield roentgenographic criteria for cervical spine injuries. Ann Emerg Med. Jul 1987;16(7):738-742. (Retrospective Review – 749 patients)
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  53. Neifeld GL, Keene JG, Hevesy G, Leikin J, Proust A, Thisted RA. Cervical injury in head trauma. J Emerg Med. May-Jun 1988;6(3):203-207. (Prospective Observational – 865 patients)
  54. Ringenberg BJ, Fisher AK, Urdaneta LF, Midthun MA. Rational ordering of cervical spine radiographs following trauma. Ann Emerg Med. Aug 1988;17(8):792-796. (Retrospective Review – 312 patients)
  55. Roberge RJ, Wears RC, Kelly M, et al. Selective application of cervical spine radiography in alert victims of blunt trauma: a prospective study. J Trauma. Jun 1988;28(6):784-788. (Prospective Observational – 467 patients)
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  59. Mower WR, Hoffman J. Comparison of the Canadian C-Spine rule and NEXUS decision instrument in evaluating blunt trauma patients for cervical spine injury. Ann Emerg Med. Apr 2004;43(4):515-517. (Letter)
  60. Wyer P. The Canadian C-SPine Rule more accurately identified cervical-spine injury in trauma than the NEXUS Low-Risk Criteria. ACP Journal Club. July/August 2004 2004;141(1):24. (Journal Review)
  61. Knopp R. Comparing NEXUS and Canadian C-Spine decision rules for determining the need for cervical spine radiography. Ann Emerg Med. Apr 2004;43(4):518-520. (Editorial)
  62. Tins BJ, Cassar-Pullicino VN. Imaging of acute cervical spine injuries: review and outlook. Clin Radiol. Oct 2004;59(10):865-880. (Systematic Review)
  63. Cooper C, Dunham CM, Rodriguez A. Falls and major injuries are risk factors for thoracolumbar fractures: cognitive impairment and multiple injuries impede the detection of back pain and tenderness. J Trauma. May 1995;38(5):692-696. (Retrospective Review – 4142 patients)
  64. Durham RM, Luchtefeld WB, Wibbenmeyer L, Maxwell P, Shapiro MJ, Mazuski JE. Evaluation of the thoracic and lumbar spine after blunt trauma. Am J Surg. Dec 1995;170(6):681-684; discussion 684-685. (Retrospective Review – 344 patients)
  65. Frankel HL, Rozycki GS, Ochsner MG, Harviel JD, Champion HR. Indications for obtaining surveillance thoracic and lumbar spine radiographs. J Trauma. Oct 1994;37(4):673-676. (Retrospective Review – 1485 patients)
  66. Hsu JM, Joseph T, Ellis AM. Thoracolumbar fracture in blunt trauma patients: guidelines for diagnosis and imaging. Injury. Jun 2003;34(6):426-433. (Retrospective Performance Assessment – 200 patients)
  67. Meldon SW, Moettus LN. Thoracolumbar spine fractures: clinical presentation and the effect of altered sensorium and major injury. J Trauma. Dec 1995;39(6):1110-1114. (Retrospective Review – 145 patients)
  68. Saboe LA, Reid DC, Davis LA, Warren SA, Grace MG. Spine trauma and associated injuries. J Trauma. Jan 1991;31(1):43-48. (Retrospective Review – 508 patients)
  69. Samuels LE, Kerstein MD. ‘Routine’ radiologic evaluation of the thoracolumbar spine in blunt trauma patients: a reappraisal. J Trauma. Jan 1993;34(1):85-89. (Retrospective Review – 756 patients)
  70. Stanislas MJ, Latham JM, Porter KM, Alpar EK, Stirling AJ. A high risk group for thoracolumbar fractures. Injury. Jan 1998;29(1):15-18. (Retrospective Review – 110 patients)
  71. Terregino CA, Ross SE, Lipinski MF, Foreman J, Hughes R. Selective indications for thoracic and lumbar radiography in blunt trauma. Ann Emerg Med. Aug 1995;26(2):126-129. (Prospective Case Control – 319 patients)
  72. Van Goethem JW, Maes M, Ozsarlak O, van den Hauwe L, Parizel PM. Imaging in spinal trauma. Eur Radiol. Mar 2005;15(3):582-590. (Systematic Review)
  73. Vaccaro AR, An HS, Lin S, Sun S, Balderston RA, Cotler JM. Noncontiguous injuries of the spine. J Spinal Disord. Sep 1992;5(3):320-329. (Prospective Observational – 372 patients)
  74. Brown RL, Brunn MA, Garcia VF. Cervical spine injuries in children: a review of 103 patients treated consecutively at a level 1 pediatric trauma center. J Pediatr Surg. Aug 2001;36(8):1107-1114. (Retrospective Review – 103 patients)
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  78. Pang D, Pollack IF. Spinal cord injury without radiographic abnormality in children--the SCIWORA syndrome. J Trauma. May 1989;29(5):654-664. (Retrospective Review – 55 patients)
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  92. Baker C, Kadish H, Schunk JE. Evaluation of pediatric cervical spine injuries. Am J Emerg Med. May 1999;17(3):230-234. (Retrospective Review – 72 patients)
  93. Diaz JJ, Jr., Gillman C, Morris JA, Jr., May AK, Carrillo YM, Guy J. Are five-view plain films of the cervical spine unreliable? A prospective evaluation in blunt trauma patients with altered mental status. J Trauma. Oct 2003;55(4):658-663; discussion 663-654. (Prospective Observational – 1006 patients)
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  100. Turetsky DB, Vines FS, Clayman DA, Northup HM. Technique and use of supine oblique views in acute cervical spine trauma. Ann Emerg Med. Apr 1993;22(4):685-689. (Retrospective Review – 83 patients)
  101. Woodring JH, Lee C. Limitations of cervical radiography in the evaluation of acute cervical trauma. J Trauma. Jan 1993;34(1):32-39. (Retrospective Review – 216 patients)
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  105. Vandemark RM. Radiology of the cervical spine in trauma patients: practice pitfalls and recommendations for improving efficiency and communication. AJR Am J Roentgenol. Sep 1990;155(3):465-472. (Systematic Review)
  106. Griffen MM, Frykberg ER, Kerwin AJ, et al. Radiographic clearance of blunt cervical spine injury: plain radiograph or computed tomography scan? J Trauma. Aug 2003;55(2):222-226; discussion 226-227. (Retrospective Review – 1199 patients)
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  108. Berne JD, Velmahos GC, El-Tawil Q, et al. Value of complete cervical helical computed tomographic scanning in identifying cervical spine injury in the unevaluable blunt trauma patient with multiple injuries: a prospective study. J Trauma. Nov 1999;47(5):896-902; discussion 902-893. (Prospective Observational – 58 patients)
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  110. Sheridan R, Peralta R, Rhea J, Ptak T, Novelline R. Reformatted visceral protocol helical computed tomographic scanning allows conventional radiographs of the thoracic and lumbar spine to be eliminated in the evaluation of blunt trauma patients. J Trauma. Oct 2003;55(4):665-669. (Prospective Observational – 1915 patients)
  111. Adelgais KM, Grossman DC, Langer SG, Mann FA. Use of helical computed tomography for imaging the pediatric cervical spine. Acad Emerg Med. Mar 2004;11(3):228-236. (Prospective Observational – 136 patients)
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  113. Brady WJ, Moghtader J, Cutcher D, Exline C, Young J. ED use of flexion-extension cervical spine radiography in the evaluation of blunt trauma. Am J Emerg Med. Oct 1999;17(6):504-508. (Retrospective Review – 451patients)
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  117. Pollack CV, Jr., Hendey GW, Martin DR, Hoffman JR, Mower WR. Use of flexion-extension radiographs of the cervical spine in blunt trauma. Ann Emerg Med. Jul 2001;38(1):8-11. (Prospective Observational – 818 patients)
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  120. D’Alise MD, Benzel EC, Hart BL. Magnetic resonance imaging evaluation of the cervical spine in the comatose or obtunded trauma patient. J Neurosurg. Jul 1999;91(1 Suppl):54-59. (Prospective Observational – 121 patients)
  121. Dickman CA, Zabramski JM, Hadley MN, Rekate HL, Sonntag VK. Pediatric spinal cord injury without radiographic abnormalities: report of 26 cases and review of the literature. J Spinal Disord. Sep 1991;4(3):296-305. (Retrospective Review – 26 patients)
  122. Frank JB, Lim CK, Flynn JM, Dormans JP. The efficacy of magnetic resonance imaging in pediatric cervical spine clearance. Spine. Jun 1 2002;27(11):1176-1179. (Retrospective Review – 102 patients)
  123. Geck MJ, Yoo S, Wang JC. Assessment of cervical ligamentous injury in trauma patients using MRI. J Spinal Disord. Oct 2001;14(5):371-377. (Retrospective Review – 89 patients)
  124. Grabb PA, Pang D. Magnetic resonance imaging in the evaluation of spinal cord injury without radiographic abnormality in children. Neurosurgery. Sep 1994;35(3):406-414; discussion 414. (Prospective Observational – 7 patients)
  125. Keiper MD, Zimmerman RA, Bilaniuk LT. MRI in the assessment of the supportive soft tissues of the cervical spine in acute trauma in children. Neuroradiology. Jun 1998;40(6):359-363. (Retrospective Review – 52 patients)
  126. Klein GR, Vaccaro AR, Albert TJ, et al. Efficacy of magnetic resonance imaging in the evaluation of posterior cervical spine fractures. Spine. Apr 15 1999;24(8):771-774. (Retrospective Review – 32 patients)
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  128. Silberstein M, Tress BM, Hennessy O. Prevertebral swelling in cervical spine injury: identification of ligament injury with magnetic resonance imaging. Clin Radiol. Nov 1992;46(5):318-323. (Retrospective Review – 27 patients)
  129. Stabler A, Eck J, Penning R, et al. Cervical spine: postmortem assessment of accident injuries--comparison of radiographic, MR imaging, anatomic, and pathologic findings. Radiology. Nov 2001;221(2):340-346. (Postmortem Experimental)
  130. Anglen J, Metzler M, Bunn P, Griffiths H. Flexion and extension views are not cost-effective in a cervical spine clearance protocol for obtunded trauma patients. J Trauma. Jan 2002;52(1):54-59. (Retrospective Cost-Effectiveness Analysis – 837 patients)
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