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<< Diagnosis And Management Of Carbon Monoxide Poisoning In The Emergency Department

Discussion Of Investigational Information

Some insurance companies have recently reclassified HBO therapy as an investigational therapy in the treatment of acute CO poisoning, which implies that they would withhold payment for its use.45 However, Medicare continues to reimburse for its use, as do some private insurance companies.46

Tight regulation of glucose with insulin is another measure that can be undertaken in the CO-poisoned patient. Although there are some data that suggest the benefit may be independent of the glucose level and accrue directly to the use of insulin, its use in this manner would be off-label.47,48

Other agents (including ketamine, dimethyl sulfoxide, and allopurinol) have been proposed as beneficial, through blockade of excitatory amino acids, antioxidant properties, or prevention of free radical formation. However, these agents are not approved for treatment of CO poisoning by the US Food and Drug Administration (FDA).49,50,51

Emergency Stroke Care, Advances and Controversies

 

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Last Modified: 11/23/2017
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